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Selected Publications

Selected Publications>>

2014：

  • Jiaojiao Xu, Siyuan Wang, Ye Chen, Guangping Chen, Zaiquan Li, Xueyan Shao, Liang Li, Wei Lu, Tianyan Zhou*(2014) Dopamine D1 receptor activation induces dehydroepiandrosterone sulfotransferase (SULT2A1) in HepG2 cells. Acta Pharmacol Sin. In press. (IF= 2.354)
  • Xingang Li, Zhigang Zhao, Liang Li, Tianyan Zhou*, Wei Lu*(2014) Pharmacokinetics, in vitro and in vivo correlation, and efficacy of exenatide microspheres in diabetic rats. Drug Deliv. Early Online. (IF= 2.015)
  • Xiwei Ji, Runtao Li, Zaiquan Li, Liang Li, Xueyan Shao, Siyuan Wang, Yin Yuan, Tianyan Zhou*, Wei Lu*(2014) Inhibition of autophosphorylation of EGFR plays an important role in the anti-breast cancer efficacy of a dithiocarbamate derivative TM208. Acta Pharmacol Sin. 35:239–247. (IF= 2.354)
  • Yu-Ping Yu , Qi Wang , Ying-Chun Liu*, Ying Xie*（2014），Molecular basis for the targeted binding of RGD-containing peptide to integrin aVb3. Biomaterials, 35(5):1667-1675. (IF=7.604).
  • Hua Zhang, Xueqing Wang, Wenbing Dai, Richard A. Gemeinhart, Qiang Zhang, Tonglei Li. (2014) Pharmacokinetics and treatment efficacy of camptothecin nanocrystals on lung metastasis. Mol. Pharm. 11(1):226-233 (IF= 4.57)
  • Zhen-Zhen Yang, Jing-Quan Li, Zhan-Zhang Wang, Da-Wen Dong, Xian-Rong Qi*Tumor-targeting dual peptides-modified cationic liposomes for delivery of siRNA and docetaxel to gliomas.Biomaterials 35 (2014) 5226-5239.
  • Kai Wu, Zhan-Zhang Wang, Dan Liu, Xian-Rong Qi*.Pharmacokinetics, brain distribution, release and blood–brain barrier transport of Shunaoxin pills. J Ethnopharmacology. 151 (2014) 1133–1140.
  • Tingting Meng, Jingquan Li, Xianrong Qi*. Preparation and evaluation of lipidmatrix nanocarrier codelivery gene and sensibilizer to elevate docetaxel antitumor. J. Chin. Pharm. Sci. 2014, 23 (3), 145–152.
  • Ling-Ran Du, Xiao-Jing Lu, Hai-Tao Guan, Yong-Jie Yang, Meng-Jie Gu, Zhuo-Zhao Zheng, Tian-Shi Lv, Zi-Guang Yan, Li Song, Ying-Hua Zou, Nai-Qi Fu, Xian-Rong Qi, Tian-Yuan Fan* (2014) Development and evaluation of liquid embolic agents based on liquid crystalline material of glyceryl monooleate.Int J Pharm. 471: 285– 296. (IF 3.867)
  • Xueqing Wang, Suxin Li, Yujie Shi, Xingxing Chuan, Ji Li, Ting Zhong, Hua Zhang, Wenbing Dai, Bing He, Qiang Zhang*(2014) The development of site-specific drug delivery nanocarriers based on receptor mediation. Journal of Controlled Release. Early on line (IF 7.633)
  • Jingkai Lu, Xingxing Chuan, Hua Zhang, Wenbing Dai, Xinglin Wang, Xueqing Wang*, Qiang Zhang* (2014) Free paclitaxel loaded PEGylated-paclitaxel nanoparticles: Preparation and comparison with other paclitaxel systems in vitro and in vivo.Int J Pharm..471 (1-2): 525-35. (IF 3.458)
  • Ju RJ, Li XT, Shi JF, Li XY, Sun MG, Zeng F, Zhou J, Liu L, Zhang CX, Zhao WY, Lu WL*(2014). Liposomes, modified with PTDHIV-1 peptide, containing epirubicin and celecoxib, to target vasculogenic mimicry channels in invasive breast cancer. Biomaterials. 2014 Aug;35(26):7610-21.
  • Li XY, Zhao Y, Sun MG, Shi JF, Ju RJ, Zhang CX, Li XT, Zhao WY, Mu LM, Zeng F, Lou JN,Lu WL*(2014).. Multifunctional liposomes loaded with paclitaxel and artemether for treatment of invasive brain glioma.Biomaterials. 2014 Jul;35(21):5591-604.
  • Wenjing Li, Xinru Li, Yajie Gao, Yanxia Zhou, Shujin Ma, Yong Zhao, Jinwen Li, Yan Liu*, Xinglin Wan, Dongdong Yin. The Inhibition Mechanism of P-glycoprotein Mediated Efflux by mPEG-PLA and Influence of PLA Chain Length on P-glycoprotein Inhibition Activity. Molecular Pharmaceutics, 2014, 11:71-80. (IF=4.57)
  • Wenbing Dai, Fang Yang, Ling Ma, Yuchen Fan, Bing He, Qihua He, Xueqing Wang, Hua Zhang, Qiang Zhang (2014) Combined mTOR inhibitor rapamycin and doxorubicin-loaded cyclic octapeptide modified liposomes for targeting integrin α3 in triple-negative breast cancer. Biomaterials. 35(20):5347-5358. (IF7.604)
  • Zhaoming Guo, Bing He, Hongwei Jin, Haoran Zhang, Wenbing Dai, Liangren Zhang, Hua Zhang, Xueqing Wang, Jiancheng Wang, Xuan Zhang, Qiang Zhang*. (2014) Targeting efficiency of RGD-modified nanocarriers with different ligand intervals in response to integrin αvβ3 clustering. Biomaterials, 35(23):6106-6117.(IF:7.604)
  • Chao Qin, Bing He, Wenbing Dai, Zhiqiang Lin, Hua Zhang, Xueqing Wang, Jiancheng Wang, Xuan Zhang, Guangji Wang, Lifang Yin, Qiang Zhang. (2014) The impact of a chlorotoxin-modified liposome system on receptor MMP-2 and the receptor-associated protein ClC-3. Biomaterials, 35(22):5908-5920. (IF:7.604)
  • Wenbing Dai, Fang Yang, Ling Ma, Yuchen Fan, Bing He, Qihua He, Xueqing Wang, Hua Zhang, Qiang Zhang. (2014) Combined mTOR inhibitor rapamycin and doxorubicin-loaded cyclic octapeptide modified liposomes for targeting integrin α3 in triple-negative breast cancer. Biomaterials, 35(20):5347-5358.(IF:7.604)
  • DefuCai, Wei Gao, Bing He, Wenbing Dai, Hua Zhang, Xueqing Wang, Jiancheng Wang; Xuan Zhang; Qiang Zhang. (2014) Hydrophobic penetrating peptide PFVYLI-modified stealth liposomes for doxorubicin delivery in breast cancer therapy. Biomaterials, 35(7):2283-2294.(IF:7.604)
  • Hua Zhang, Xueqing Wang, Wenbing Dai, Richard A. Gemeinhart, Qiang Zhang*, Tonglei Li. (2014) Pharmacokinetics and treatment efficacy of camptothecinnanocrystals on lung metastasis. Molecular Pharmaceutics. 11(1):226-233，(IF:4.57)
  • Zhiqiang Lin, Wei Gao, Hongxiang Hu, KunMa , Bing He ,Wenbing Dai, XueqingWang,JianchengWang , Xuan Zhang , Qiang Zhang*. (2014) Novel thermo-sensitive hydrogel system with paclitaxel nanocrystals:High drug-loading, sustained drug release and extended local retentionguaranteeing better efficacy and lower toxicity. Journal of Controlled Release, 174 : 161–170 (IF:7.633)
  • Feng Q, Yu MZ, Wang JC*, Hou WJ, Gao LY, Ma XF, Pei XW, Niu YJ, Liu XY, Qiu C, Pang WH, Du LL, Zhang Q. Synergistic inhibition of breast cancer by co-delivery of VEGF siRNA and paclitaxel via vapreotide-modified core-shell nanoparticles. Biomaterials. 2014 Mar; 35(18):5028-38.(IF:7.604)
  • Gao LY, Liu XY, Chen CJ, Wang JC*, Feng Q, Yu MZ, Ma XF, Pei XW, Niu YJ, Qiu C,Pang WH, Zhang Q. Core-Shell type lipid/rPAA-Chol polymer hybrid nanoparticles for in vivo siRNA delivery.Biomaterials. 2014 Feb;35(6):2066-78.(IF:7.604)

 

2013：

  • Mengyao Li, Hanqing Li, Xiaoliang Cheng, Xipei Wang, Liang Li, Tianyan Zhou*, Wei Lu*(2013) Preclinical Pharmacokinetic/Pharmacodynamic Models to Predict Schedule-Dependent Interaction between Erlotinib and Gemcitabine. Pharm Res. 30(5):1400-1408. (IF= 4.742)
  • Qiong Wu, Mengyao Li, Hanqing Li, Chenhui Deng, Liang Li, Tianyan Zhou*, Wei Lu*(2013) Pharmacokinetic and pharmacodynamic study of erlotinib based upon phosphorylated epidermal growth factor receptor and tumor volume in human non-small cell lung cancer xenograft mouse mode. Acta Pharmacol Sin. 34:1427–1436. (IF= 2.354)
  • Xiaoliang Cheng, Liping Guo, Zaiquan Li, Liang Li, Tianyan Zhou*, Wei Lu*(2013) A HPLC method for simultaneous determination of 5-aminoimidazole-4-carboxamide riboside and its active metabolite 5-aminoimidazole-4-carboxamide ribotide in tumor-bearing nude mice plasma and its application to pharmacokinetics study. J Chromatogr B. 915–916:64–70. (IF= 2.487)
  • Tianyan Zhou, Chaoqun Huang, Yue Chen, Jiaojiao Xu, Preeti Devaraya Shanbhag, Guangping Chen (2013) Methamphetamine Regulation of Sulfotransferase 1A1 and 2A1 Expression in Rat Brain Sections. Neurotoxicology. 34:212-218. (IF 2.652)
  • Hua Zhang, Yuan Meng, Xueqing Wang, Wenbing Dai, Xinglin Wang, Qiang Zhang. (2013) Pharmaceutical and pharmacpkinetic characteristics of different types of fenofibrate nanocrystals prepared by different bottom-up approuches. Drug Del.. DOI:10.3109/10717544.2013.865815(IF= 2.015)
  • Luo LM, Huang Y, Zhao BX, Zhao X, Duan Y, Du R, Yu KF, Song P, Zhao Y, Zhang X*(2013), Zhang Q. Anti-tumor and anti-angiogenic effect of metronomic cyclic NGR-modified liposomes containing paclitaxel. Biomaterials. 2013 Jan;34(4):1102-14.(IF=7.604)
  • Gao Wei, Xiang Bai, Meng Tingting, Liu Feng, Qi Xianrong*. Chemotherapeutic drug delivery to cancer cells using a combination of folate targeting and tumor microenvironment-sensitive polypeptides. Biomaterials. 2013, 34: 4137-4149.
  • Dong Dawen, Xiang Bai, Gao Wei, Yang Zhenzhen, Li Jingquan Li, Qi Xianrong*. pH-responsive complexes using prefunctionalized polymers for synchronous delivery of doxorubicin and siRNA to cancer cells. Biomaterials. 2013, 34: 4849-4859.
  • Xiang Bai, Dong Dawen, Shi Nianqiu, Gao Wei, Yang Zhenzhen, Cui Yi, Cao Deying, Qi Xianrong Qi*. PSA-responsive and PSMA-mediated multifunctional liposomes for targeted therapy of prostate cancer. Biomaterials. 2013, 34: 6976-6991.
  • Zhen-Zhen Yang, Yan-Qing Zhang, Zhan-Zhang Wang, Kai Wu, Jin-Ning Lou, Xian-Rong Qi*. Enhanced brain distribution and pharmacodynamics of rivastigmine by liposomes following intranasal administration. International Journal of Pharmaceutics 452 (2013) 344– 354.
  • Zhanzhang Wang, Zhenzhen Yang, Xianrong Qi*. Hematological and pathological toxicity of antiHER2/neu-peptide-mimetic modified paclitaxel bovine serum albumin nanoparticles J. Chin. Pharm. Sci. 2013, 22 (5), 441–442 448.
  • Dong Da-Wen; Tong Shu-Wen; Qi Xian-Rong*, Comparative studies of polyethylenimine-doxorubicin conjugates with pH-sensitive and pH-insensitive linkers, J Biomed Mater Res Part A, Journal of Biomedical Materials Research, Part A (2013), 101A(5), 1336-1344.
  • Xiao-Jing Lu, Yuan Zhang, Dai-Chao Cui, Wen-Jing Meng, Ling-Ran Du, Hai-Tao Guan, Zhuo-Zhao Zheng, Nai-Qi Fu, Tian-Shi Lv, Li Songb,Ying-Hua Zou, Wan-Liang Lu, Tian-Yuan Fan* (2013) Research of novel biocompatible radiopaque microcapsules forarterial embolization. Int J Pharm. 452: 211– 219. (IF 3.867)
  • Bo Zhao, Xue-Qing Wang*, Xiao-You Wang, Hua Zhang, Wen-Bing Dai, Jun Wang, Zhen-Lin Zhong, Hou-Nan Wu*and Qiang Zhang* (2013)Nanotoxicity comparison of four amphiphilic polymeric micelles with similar hydrophilic or hydrophobic structure.Particle and Fibre Toxicology. 10:47. (IF 9.178)
  • Chao Yu, Bing He, Meng-Hua Xiong, Hua Zhang, Lan Yuan, Ling Ma, Wen-Bing Dai, Jun Wang, Xing-Lin Wang, Xue-Qing Wang*, Qiang Zhang* (2013) The effect of hydrophilic and hydrophobic structure of amphiphilic polymeric micelles on their transport in epithelial MDCK cell. Biomaterials. 34 (26): 6284-6298. (IF 7.604)
  • Ma X, Zhou J, Zhang CX, Li XY, Li N, Ju RJ, Shi JF, Sun MG, Zhao WY, Mu LM, Yan Y, Lu WL*. Modulation of drug-resistant membrane and apoptosis proteins of breast cancer stem cells by targeting berberine liposomes. Biomaterials. 2013 Jun;34(18):4452-65.
  • Chao Fan, Xinru Li, Yanxia Zhou, Yong Zhao, Shujin Ma, Wenjing Li, Yan Liu*, Guiling Li. Enhanced topical delivery of tetrandrine by ethosomes for treatment of arthritis. BioMed Research International. Volume2013, Article ID 161943, 13 pages(IF=2.88)
  • Bo Zhao, Xueqing Wang, Xiaoyou Wang, Hua Zhang, Wenbing Dai, Jun Wang, ZhenlinZhong, Hounan Wu, Qiang Zhang. (2013) Nanotoxicity comparison of four amphiphilic polymeric micelles with similar hydrophilic or hydrophobic structure. Particle and Fibre Toxicology. Doi: 10.1186/1743-8977-10-47.(IF:9.178)
  • Chao Yu, Bing He, MenghuaXiong, Hua Zhang, Lan Yuan, Ling Ma, Wenbing Dai, Jun Wang, Xinglin Wang, Xueqing Wang, Qiang Zhang. (2013) The effect of hydrophilic and hydrophobic structure of amphiphilic polymeric micelles on their transport in epithelial MDCK cells. Biomaterials, 34(26): 6284-6298.(IF:7.604)
  • Bing He, Ping Lin, ZengrongJia, Wenwen Du, Wei Qu, Lan Yuan, Wenbing Dai, Hua Zhang, Xueqing Wang, Jiancheng Wang, Xuan Zhang, Qiang Zhang. (2013) The transport mechanisms of polymer nanoparticles in Caco-2 epithelial cells. Biomaterials, 34(25):6082-6098. (IF:7.604)
  • Bing He, ZengrongJia, Wenwen Du, Cao Yu, Yuchen Fan, Wenbing Dai, Lan Yuan, Hua Zhang, Xueqing Wang, Jiancheng Wang, Xuan Zhang, Qiang Zhang. (2013) The transport pathways of polymer nanoparticles in MDCK epithelial cells Biomaterials, 34(17):4309-4326.(IF:7.604)
  • Yuchen Fan, Wenwen Du, Bing He, Fengying Fu, Lan Yuan, Hounan Wu, Wenbing Dai, Hua Zhang, Xueqing Wang, Jiancheng Wang, Xuan Zhang, Qiang Zhang. (2013) The reduction of tumor interstitial fluid pressure by liposomal imatinib and its effect on combination therapy with liposomal doxorubicin. Biomaterials, 34(9):2277-2288. (IF:7.604)
  • Wenwen Du, Yuchen Fan, Nan Zheng, Bing He, Lan Yuan, Hua Zhang, Xueqing Wang, Jiancheng Wang, Xuan Zhang, Qiang Zhang. (2013) Transferrin receptor specific nanocarriers conjugated with functional 7peptide for oral drug delivery. Biomaterials, 34(3):794-806. (IF:7.604)
  • Chao Qin,BingHe,WenbingDai,Hua Zhang, Xueqing Wang, Jiancheng Wang, XuanZhang,Guangji Wang, Lifang Yin, Qiang Zhang. (2013) Inhibition of Metastatic Tumor Growth and Metastasis via TargetingMetastatic Breast Cancer by Chlorotoxin-Modified Liposomes. Molecular Pharmaceutics. dx.doi.org/10.1021/mp400691z (IF:4.57)
  • Zhaohui Wang, Yang Yu, Wenbing Dai, Jingrong Cui, Hounan Wu, Lan Yuan, Hua Zhang, Xueqing Wang, Jiancheng Wang, Xuan Zhang, Qiang Zhang. (2013) A specific peptide ligand-modified lipid nanoparticle carrier for the inhibition of tumor metastasis growth. Biomaterials, 34(3):756-764. (IF:7.604)
  • Cheng-Jun Chen, Jian-Cheng Wang*, En-Yu Zhao, Ling-Yan Gao, Qiang Feng, Xiao-Yan Liu, Zhi-Xia Zhao, Xiao-Fei Ma, Wen-Jie Hou, Liang-Ren Zhang, Wan-Liang Lu, Qiang Zhang. Self-assembly cationic nanoparticles based on cholesterol-grafted bioreducible poly(amidoamine) for siRNA delivery. Biomaterials. 2013 Jul;34(21):5303-16

 

2012：

  • Xuan Zhou, Dewei Shang, Tianlan Zhang, Liang Li,Tianyan Zhou*, Wei Lu* (2012) Modeling of Angiotensin II-Angiotensin-(1-7) Counterbalance in Disease Progression in Spontaneously Hypertensive Rats Treated With/Without Perindopril. Pharmacol Res. 66:177-184. (IF= 4.346)
  • Xingang Li, Liang Li, Xipei Wang, Yupeng Ren, Tianyan Zhou*, Wei Lu* (2012)Application of Model-Based Methods to Characterize Exenatide-Loaded Double-Walled Microspheres: In Vivo Release, Pharmacokinetic/Pharmacodynamic Model, and In Vitro and In Vivo Correlation. J Pharm Sci. 101(10):3946-3961. (IF= 3.055)
  • Jiaojiao Xu, Ye Chen, Liang Li, Zaiquan Li, Chenai Wang, Tianyan Zhou*, Wei Lu* (2012)An improved HPLC method for the quantitation of 3′-phosphoadenosine 5′-phosphate (PAP) to assay sulfotransferase enzyme activity in HepG2 cells.J Pharmaceut Biomed. 62:182-186. (IF= 2.967)
  • Tianyan Zhou, Yue Chen, Chaoqun Huang, Guangping Chen (2012) Caffeine induction of sulfotransferases in rat liver and intestine. J Appl Toxicol.32:804-809. (IF= 2.478)
  • Xiwei Ji, Ye Chen, Runtiao Li, Tianyan Zhou*, Wei Lu* (2012)A high-sensitivity LC-MS/MS method for determination of 4-methyl-piperazine-1-carbodithioc acid 3-cyano-3, 3-diphenylpropyl ester hydrochloride in rat plasma and its application to pharmacokinetics study. Biomed Chromatogr. 26:1196-1201.(IF= 1.966)
  • Xingang Li, Liang Li, Xuan Zhou, Ye Chen, Yupeng Ren, Tianyan Zhou*, Wei Lu* (2012)Pharmacokinetic/pharmacodynamic studies for exenatide in diabetic rats. Acta Pharmacol Sin.33:1379-1386. (IF= 1.953)
  • Liang Li, Zaiquan Li, Chenhui Deng, Miaoran Ning,; Hanqing Li, Shanshan Bi, Tianyan Zhou*, Wei Lu* (2012) Mechanism-based Pharmacokinetic/Pharmacodynamic Model for CYP3A1/2 Induction by Dexamethasone in Rats. Acta Pharmacol Sin.33:127-136. (IF= 1.953)
  • Zhao S, Dai W, He B, Wang J, He Z, Zhang X*, Zhang Q*(2012). Monitoring the transport of polymeric micelles across MDCK cell monolayer and exploring related mechanisms. J Control Release. 2012 Mar 28;158(3):413-23. (IF=7.633)
  • Zhao BX, Zhao Y, Huang Y, Luo LM, Song P, Wang X, Chen S, Yu KF, Zhang X*, Zhang Q(2012). The efficiency of tumor-specific pH-responsive peptide-modified polymeric micelles containing paclitaxel. Biomaterials. 2012 Mar;33(8):2508-20. (IF=7.604)
  • ZZ Yang, ZZ Wang, K Wu, XR Qi*. Tissue Distribution and Pharmacodynamics of Rivastigmine after Intranasal and Intravenous Administration in Rats. Current Alzheimer Res. 2012, 9(3)：315-325.
  • Shu-Wen Tong, Bai Xiang, Da-Wen Dong, Xian-Rong Qi*. Enhanced antitumor efficacy and decreased toxicity by self-associated docetaxel in phospholipid-based micelles. International Journal of Pharmaceutics 434 (2012): 413– 419.
  • Nian-Qiu Shi, Wei Gao, Bai Xiang, Xian-Rong Qi*. Enhancing cellular uptake of activable cell-penetrating peptide–doxorubicin conjugate by enzymatic cleavage. International Journal of Nanomedicine 2012:7 1613–1621.

 

  • Dai-Chao Cui,Wan-Liang Lu, Er-A Sa, Meng-Jie Gu, Xiao-Jing Lu, Tian-Yuan Fan* (2012) Poly(acrylic acid) microspheres loaded with lidocaine: Preparation and characterization for arterial embolization. Int J Pharm. 436: 527– 535. (IF 3.867)
  • Chao Zhou, Daichao Cui, Yuan Zhang, Huiyan Yuan, Tianyuan Fan* (2012) Preparation and characterization of ketoprofen-loaded microspheres for embolization. J Mater Sci-Mater M. 23:409-418. (IF 2.48)
  • Xue-Qing Wang, Qiang Zhang* (2012) pH-sensitive polymeric nanoparticles to improve oral bioavailability of peptide/protein drugs and poorly water-soluble drugs. European Journal of Pharmaceutics and Biopharmaceutics. 82 (2): 219-229. (IF 3.826)
  • Xueqing Wang, Javed Iqbal, Deni Rahmat, Andreas Bernkop-Schnürch* (2012) Preactivated thiomers: Permeation enhancing properties. International Journal of Pharmaceutics. 438 (1-2): 217-224. (IF 3.458)
  • Xingwei Chen, Xinru Li, Yanxia Zhou, Xiaoning Wang, Yanhui Zhang Yating Fan, Yanqing Huang, Yan Liu*.Chitosan-based Thermosensitive Hydrogel as a Promising Ocular Drug Delivery System: Preparation, Characterization and In Vivo Evaluation. Journal of Biomaterials Applications, 2012, 27(4): 391-402. (IF=2.64)
  • Na Li, Xinru Li, Yanxia Zhou, Wenjing Li, Yong Zhao, Shujin Ma, Jinwen Li, Yajie Gao, Yan Liu*, Xinglin Wang, Dongdong Yin. The use of polyion complex micelles to enhance the oral delivery of salmon calcitonin and transport mechanism across the intestinal epithelial barrier. Biomaterials, 2012,33(34):8881-8892. (IF=7.604)
  • Guiling Li, Yating Fan, Chao Fan, Xinru Li, Xiaoning Wang, Mei Li, Yan Liu*. Tacrolimus-loaded ethosomes: Physicochemical characterization and in vivo evaluation. European Journal of Pharmaceutics and Biopharmaceutics, 2012, 82:49-57. (IF=3.826)
  • Guiling Li, Yating Fan, Xinru Li, Xiaoning Wang, Yanfang Li, Yan Liu*, Mei Li. In vitro and in vivo evaluation of a simple microemulsion formulation for propofol. International Journal of Pharmaceutics, 2012, 425:53–61.(IF=3.458)
  • Wenbing Dai, Tingyuan Yang, Yiguang Wang, Xueqing Wang, Jiancheng Wang, Xuan Zhang, Qiang Zhang (2012) Peptide PHSCNK as an integrin α5β1 antagonist targets stealth liposomes to integrin-overexpressing melanoma. Nanomed-nanotechnol. 8 (7): 1152–1161. (IF6.692)
  • Wenbing Dai, Wu Jin, Junlin Zhang, Xueqing Wang, Jiancheng Wang, Xuan Zhang, You Wan, Qiang Zhang (2012) Spatiotemporally Controlled Co-delivery of Anti-vasculature Agent and Cytotoxic Drug by Octreotide-Modified Stealth Liposomes. Pharm Res. 29(10):2902–2911. (IF4.093)
  • Zhaohui Wang, Yang Yu, Wenbing Dai, Jingkai Lu, Jingrong Cui, Hounan Wu, Lan Yuan, Hua Zhang, Xueqing Wang, Jiancheng Wang, Xuan Zhang, Qiang Zhang. (2012)The use of a tumor metastasis targeting peptide to deliver doxorubicin-containing liposomes to highly metastatic cancer. Biomaterials, 33(33): 8451-8460. (IF:7.404)
  • Zhaohui Wang, Yang Yu, Jie Ma, Haoran Zhang, Hua Zhang, Xueqing Wang, Jiancheng Wang, Xuan Zhang, Qiang Zhang. (2012) LyP-1 Modification To Enhance Delivery of Artemisinin or Fluorescent Probe Loaded Polymeric Micelles to Highly Metastatic Tumor and Its Lymphatics.Molecular Pharmaceutics, 9(9):2646-2657.(IF:4.782)
  • Nan Zheng, Wenbing Dai, Wenwen Du, Haoran Zhang, Liandi Lei, Hua Zhang, Xueqing Wang, Jiancheng Wang, Xuan Zhang, JinmingGao, Qiang Zhang. (2012) A Novel Lanreotide-Encoded Micelle System Targets Paclitaxel to the Tumors with Overexpression of Somatostatin Receptors. Molecular Pharmaceutics, 9(5):1175-1188. (IF:4.782)
  • Wenbing Dai, Tingyuan Yang, Yiguang Wang, Xueqing Wang, Jiancheng Wang, Xuan Zhang, Qiang Zhang, (2012) Peptide PHSCNK as an integrin α5β1 antagonist targets stealth liposomesto integrin-overexpressing melanoma. Nanomedicine: Nanotechnology, Biology, and Medicine, 8 (7) 1152–1161 (IF:6.692)
  • Yang Zhang, Hua Zhang , Xueqing Wang, Jiancheng Wang, Xuan Zhang, Qiang Zhang. (2012) The eradication of breast cancer and cancer stem cells using octreotidemodifiedpaclitaxel active targeting micelles and salinomycin passive targeting micelles. Biomaterials. 33:679-691. (IF:7.404)
  • Wenbing Dai, Wu Jin,Junlin Zhang,Xueqing Wang,Jiancheng Wang,Xuan Zhang, You Wan,Qiang Zhang. (2012) Spatiotemporally Controlled Co-delivery of Anti-vasculatureAgent and Cytotoxic Drug by Octreotide-ModifiedStealth Liposomes. Pharm Res, 29(10):2902–2911.(IF:4.093)
  • Liang Liang, Song-Wen Lin, Wenbin Dai, Jing-Kai Lu, Ting-Yuan Yang, Yu Xiang, Yang Zhang, Run-Tao Li*, Qiang Zhang*.(2012) Novel cathepsin B-sensitive paclitaxel conjugate: higher water solubility, better efficacy and lower toxicity.Journal of Controlled Release，160（3）:618-629. (IF:6.499)
  • Shan Shan Zhao,Wenbing Dai, Bing He, JianchengWang, ZhongguiHe, XuanZhang*, QiangZhang* (2012) Monitoring the transport of polymeric micelles across MDCK cell monolayer and exploring related mechanisms.J Control Release. 158(3):413-23 (IF:6.499)
  • Xue-Qing Wang, Qiang Zhang (2012) pH-sensitive polymeric nanoparticles to improve oral bioavailability of peptide/protein drugs and poorly water-soluble drugs.European Journal of Pharmaceutics and Biopharmaceutics, 82(2): 219-229.(IF: 4.269)
  • Tingyuan Yang, Yiguang Wang, Zaiquan Li, Wenbing Dai, Jie Yin, Liang Liang, Xue Ying, Shufeng Zhou, Jiancheng Wang, Xuan Zhang, Qiang Zhang. (2012) Targeted delivery of a combination therapy consisting of combretastatin A4 and low-dose doxorubicin against tumor neovasculature. Nanomedicine: Nanotechnology, Biology, and Medicine, 8 (1) 81–92 (IF:6.692)
  • Zhao ZX, Gao SY, Wang JC*, Chen CJ, Zhao EY, Hou WJ, Feng Q, Gao LY, Liu XY, Zhang LR*, Zhang Q. Self-assembly nanomicelles based on cationic mPEG-PLA-b-Polyarginine(R15) triblock copolymer for siRNA delivery. Biomaterials. 2012,33(28):6793-807.
  • Enyu Zhao, Zhixia Zhao, Jiancheng Wang*, Chunhui Yang,* Chengjun Chen, Lingyan Gao,Qiang Feng, Wenjie Hou, Mingyuan Gao* and Qiang Zhang. Surface engineering of gold nanoparticles for in vitro siRNA delivery. Nanoscale, 2012,4(16): 5102–5109.
  • Xiao-Mei Tao, Jian-cheng Wang*, Jia-bao Wang, Qiang Feng, Shan-yun Gao, Liang-Ren Zhang , Qiang Zhang*. Enhanced anticancer activity of gemcitabine coupling with conjugated linoleic acid against human breast cancer in vitro and in vivo, European Journal of Pharmaceutics and Biopharmaceutics 2012,82(2):401-409

2011：

  • Hanqing Li, Mengyao Li, Zaiquan Li, Liang Li, Shanshan Bi, Chenhui Deng, Rui Chen, Tianyan Zhou*, Wei Lu* (2011) New synthetic route of two active isomeric metabolites of erlotinib and their bioactivity studies against several tumor cell lines. Chinese J Chem. 29(8):1709-1714. (IF= 0.755)
  • Dewei Shang, Xipei Wang, Xiutai Zhao, Fengming Huang, Ganzhong Tian, Wei Lu*, Tianyan Zhou* (2011) Simultaneous determination of nitrendipine and hydrochlorothiazide in spontaneously hypertensive rat plasma using HPLC with on-line solid-phase extraction. J Chromatogr B. 879:3459-3464．(IF= 2.888)
  • Hua Zhang; Hollis P.Cristine; Qiang Zhang; Tonglei Li (2011) Preparation and antitumor study of camptothecin nanocrystals. Inter. J. Pharm.. 415(1-2): 293-300 (IF= 3.607)
  • ZX Lv, LT Liu, XR Qi*. Development of small interfering RNA delivery system using PEI-PEG-APRPG polymer for antiangiogenic vascular endothelial growth factor tumor-targeted therapy. Int J Nanomedicine 2011, 6:1661-1673
  • DX Ma，NQ Shi，XR Qi*. Distinct transduction modes of arginine-rich cell-penetrating peptides for cargo delivery into tumor cells. Int J Pharm 2011,419（1-2）：200-208.
  • W zhao, S Zhuang, XR Qi*. Comparative study of the in vitro and in vivo characteristics of cationic and neutral liposomes. Int J Nanomed 2011(6)3087-3098.
  • Xue-qing Wang, Jie-ming Fan, Ya-ou Liu, Bo Zhao, Zeng-rong Jia, Qiang Zhang* (2011) Bioavailability and pharmacokinetics of sorafenib suspension, nanoparticles and nanomatrix for oral administration to rat. International Journal of Pharmaceutics. 419 (1-2): 339-346. (IF 3.458)
  • Xiaoning Wang, Xinru Li,Yanxia Zhou, Chao Fan, Wenjing Li, Shujin Ma, Yating Fan, Yanqing Huang, Na Li,Yan Liu*. Synthesis, characterization and biocompatibility of poly(2-ethyl-2-oxazoline)-poly(D,L-lactide)-poly(2-ethyl-2-oxazoline)hydrogels. Acta Biomaterialia, 2011, 7: 4149-4159. (IF=4.865)
  • Yating Fan, Xinru Li, Yanxia Zhou, Chao Fan, Xiaoning Wang, Yanqing Huang, Yan Liu*. Improved intestinal delivery of salmon calcitonin by water-in-oil microemulsions. International Journal of Pharmaceutics,2011,416:323-330. (IF=3.35)
  • Xinru Li, Yanhui Zhang, Yating Fan, Yanxia Zhou, Xiaoning Wang, Chao Fan, Yan Liu*and Qiang Zhang. Preparation and evaluation of novel mixed micelles as nanocarriers for intravenous delivery of propofol. Nanoscale Research Letters, 2011,6:275. (IF=2.726)
  • Xinru Li, Yuanting Yue, Yanxia Zhou, Yating Fan, Chao Fan, Yanqing Huang, Fei Wu, Yan Liu*. An oil-free microemulsion for intravenous delivery of diallyl trisulfide: Formulation and evaluation.International Journal of Pharmaceutics, 2011, 407:158-166. (IF=3.35)
  • Xiang Yu,Liang Liang, XueqingWang,JianchengWang, XuanZhang, QiangZhang. (2011) Chloride channel-mediated brain glioma targeting of chlorotoxin-modified doxorubicine-loaded liposomes.J Control Release. 152(3): 402-410.(IF:7.164)
  • Yiguang Wang, TingyuanYang, XueqingWang, WenbingDai,Jiancheng Wang, XuanZhang, ZaiquanLi, QiangZhang. (2011) Materializing sequential killing of tumor vasculature and tumor cells via targeted polymeric micelle system.J Control Release,149 (3):299-306. (IF: 7.164)
  • Feihu Wang, DianruiZhang*,QiangZhang*, YuxuanChen, DandanZheng, LeileiHao, CunxianDuan, LejiaoJia, GuangpuLiu, YueLiu. (2011) Synergistic effect of folate-mediated targeting and verapamil-mediated P-gp inhibition with paclitaxel -polymer micelles to overcome. Biomaterials,32(35):9444-9456. (IF:7.882)
  • Yuan Zhang, Xueqing Wang, Jiancheng Wang, Xuan Zhang, Qiang Zhang. (2011) Octreotide-modified polymeric micelles as potential carriers for targeted docetaxel delivery to somatostatin receptor overexpressing tumor cells. Pharm Res,28(5):1167-1178. (IF:4.456)

2010：

  • Zhang X, Ogl？cka K, Sandgren S, Belting M, Esbj？rner EK, Nordén B, Gr？slund A(2010).Dual functions of the human antimicrobial peptide LL-37-Target membrane perturbation and host cell cargo delivery. Biochim Biophys Acta. 2010 Dec; 1798(12):2201-8.(IF=4.647)
  • Ke XY, Zhao BJ, Zhao X, Wang Y, Huang Y, Chen XM, Zhao BX, Zhao SS, Zhang X*(2010), Zhang Q. The therapeutic efficacy of conjugated linoleic acid - paclitaxel on glioma in the rat. Biomaterials. 2010 Aug; 31(22):5855-64. (IF=7.882)
  • Tianyan Zhou, Chaoqun Huang, Yue Chen, Preeti Shanbhag, Guangping Chen (2010) Methamphetamine regulation of sulfotransferases in rat liver and brain. Am J Pharmacol Toxicol. 5(3):125-132.

 

  • Tianyan Zhou, Xinming Li, Magdeline Tao Tao Ng, Yifan Wang, Ngee Mien Quek, Ji Luo, Weixing Yuan, Choon-Hong Tan, Huaqiang Zeng, Tianhu Li (2009) Synthesis and Characterization of Circular Structures of i-Motif Tagged with Fluoresceins.Bioconjugate Chem. 20(4):644-647.(IF= 4.350)

 

  • Tianyan Zhou, Yifan Wang, Xinming Li, Qiang Zhang, Tianhu Li (2006) Synthesis and characterization of a fluorescein-labeled circular G-quadruplex. B Chem Soc Jpn. 79(8):1300-1302. (IF= 1.505)
  • Tianyan Zhou, Guoshu Chen, Yifan Wang, Qiang Zhang, Ming Yang, Tianhu Li (2004)Synthesis of unimolecularly circular G-quadruplexes as prospective molecular probes.Nucleic Acids Res. 32(21):e173/1-e173/9.(IF= 7.260)
  • Tianyan Zhou, Qiang Zhang, Guoshu Chen, Zhongyuan Zhou (2004) Redetermination of 4-nitrobenzenesulfonamide. Acta Crystallogra E. E60(10):o1767-o1768.(IF= 0.491)
  • Ying X, Wen H, Lu WL*, Du J, Guo J, Tian W, Men Y, Zhang Y, Li RJ, Yang TY, Shang DW, Lou JN, Zhang LR, Zhang Q. Dual-targeting daunorubicin liposomes improve the therapeutic efficacy of brain glioma in animals. J Control Release. 2010 Jan; 141(2): 183-192
  • Liu Y,Lu WL*, Guo J, Du J, Li T, Wu JW, Wang GL, Wang JC, Zhang X, Zhang Q.A potential target associated with both cancer and cancer stem cells: A combination therapy for eradication of breast cancer using vinorelbine stealthy liposomes plus parthenolide stealthy liposomes. J Control Release. 2008 Jul 2;129(1):18-25
  • Yanhui Zhang, Xinru Li, Yanxia Zhou, Yating Fan, Xiaoning Wang, Yanqing Huang, Yan Liu*. Cyclosporine A-loaded Poly(ethylene glycol)-b-poly(D,L-lactic acid) Micelles: Preparation,in vitro and in vivo Characterization and Transport Mechanism across the Intestinal Barrier. Molecular Pharmaceutics, 2010,7(4):1169-1182. (IF=5.400)
  • Xinru Li, Pingzhu Li, Yanhui Zhang, Yanxia Zhou, Xingwei Chen, Yanqing Huang, Yan Liu*. Novel mixed polymeric micelles for enhancing delivery of anticancer drug and overcoming multidrug resistance in tumor cell lines simultaneously.Pharm Res. 2010,27(8):1498-1511. (IF=4.456)
  • Wang Fei; Li Xinru; Zhou Yanxia; Zhang Yanhui; Chen Xingwei; Yang Jingxiong; Huang Yanqing; Yan Liu*. Novel Nanoscaled Polyion Complex Micelles for Targeted Delivery of Recombinant Hirudin to Platelets Based on Cationic Copolymer. Molecular Pharmaceutics, 2010, 7(3):718-726. (IF=5.400)
  • Yanhui Zhang, Xinru Li, Yanxia Zhou, Xiaoning Wang, Yating Fan, Yanqing Huang, Yan Liu*. Preparation and Evaluation of Poly(Ethylene Glycol)–Poly(Lactide) Micelles as Nanocarriers for Oral Delivery of Cyclosporine A. Nanoscale Resrarch Letters, 2010, 5:917-925.(IF=2.557)
  • Xinru Li, Xiaoyan Li, Yanxia Zhou, Yan Liu？, Ming Guo, Qingfen Zhu, Yuanchao Xie, Zhiyun Fan. Development of patch and spray formulations for enhancing topical delivery of sinomenine hydrochloride. Journal of Pharmaceutical Sciences, 2010, 99(4)：1790-1799 (IF=3.031)
  • Wenbing Dai; Tingyuan Yang; Xueqing Wang Xuan Zhang, Jiancheng Wang, Qiang Zhang (2010) PHSCNK-Modified and doxorubicin-loaded liposomes as a dual targeting system to integrin-overexpressing tumor neovasculature and tumor. J Drug Target 18(4): 254-263. (IF2.885)
  • FenghuaXu, Guiyang Liu, Qiang Zhang, Ronald A. Siegel. (2010) A comparative study on two phenylboronic acid based glucose-sensitive hydrogels. Frontiers in Bioscience, E2, 657-667. (IF:4.048)
  • Jiang J, Yang SJ, Wang JC*, Yang LJ, Xu ZZ, Yang T, Liu XY, Zhang Q. Sequential treatment of drug-resistant tumors with RGD-modified liposomes containing siRNA or doxorubicin. European Journal of Pharmaceutics and Biopharmaceutics. 2010,76(2):170-8.
  • Zhang YF, Wang JC*, Bian DY, Zhang X, Zhang Q., Targeted delivery of RGD-modified liposomes encapsulating both combretastatin A-4 and doxorubicin for tumor therapy: In vitro and in vivo studies，European Journal of Pharmaceutics and Biopharmaceutics, 2010, 74: 467-473

 

 

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