Wenbing Dai, PhD, Assistant Researcher
Tel/Fax:010-82805724
Email:pawpaw009@126.com
Got his bachelor degree from Department of Pharmaceutics, College of Pharmacy, Wuhan University in 2003; Got his master degree from Department of Pharmaceutics, College of Pharmacy, Wuhan University in 2006;Got his doctor degree from Department of Pharmaceutics, School of Pharmaceutical Science, Peking University in 2009;Engaged in his postdoctoral fellow in School of Basic Medical Sciences, Peking University from 2009 to 2012; Has been working in Department of Pharmaceutics, School of Pharmaceutical Science, Peking University since 2012.
He has taken part in several research programs, the on-going programs including the National Basic Research Program (973 Program). He has published about ten articles and applied five patents.
Research Interesting:
Tumor targeting drug delivery system;Nanotechnology to improve the oral bioavailability of poor soluble drugs;Research and Development of Novel delivery systems;
Publications:
1.Dai W, Yang T, Wang Y, Wang X, Wang J, Zhang X, Zhang Q*. PHSCNK-Modified and doxorubicin-loaded liposomes as a dual targeting system to integrin-overexpressing tumor neovasculature and tumor cells. J drug target, 2010, 18: 254.
2.Dai W, Yang T, Wang Y, Wang X, Wang J, Zhang X, Zhang Q*.Peptide PHSCNK as an integrin α5β1 antagonist targets stealth liposomes to integrin-overexpressing melanoma. Nanomedicine: NMB, 2012, 8(7):1152-61.
3.He S, Cui Z, Mei D, Zhang H, Wang X, Dai W*, Zhang Q. A Cremophor-free self-microemulsified delivery system for intravenous injection of teniposide: evaluation in vitro and in vivo. AAPS PharmSciTech. 2012, 13(3):846-52.
4.Dai W, Jin W, Zhang J, Wang X, Wang J, Zhang X, Wan Y, Zhang Q. Spatiotemporally Controlled Co-delivery of Anti-vasculature Agent and Cytotoxic Drug by Octreotide-Modified Stealth Liposomes. Pharm Res. 2012, 29(10):2902-11.
5.Zhao S, Dai W, He B, Wang J, He Z, Zhang X, Zhang Q*. Monitoring the transport of polymeric micelles across MDCK cell monolayer and exploring related mechanisms. J Control Release, 2012, 160(3): 413-23
6.Zheng N, Dai W, Du W, Zhang H, Lei L, Zhang H, Wang X, Wang J, Zhang X, Gao J, Zhang Q*. A Novel Lanreotide-Encoded Micelle System Targets Paclitaxel to the Tumors with Overexpression of Somatostatin Receptors. Mol. Pharmaceutics, 2012, 9:1175.
7.Liang L, Lin S, Dai W, Lu J, Yang T, Xiang Y, Zhang Y, Li R, Zhang Q*. Novel cathepsin B-sensitive paclitaxel conjugate: higher water solubility, better efficacy and lower toxicity. J Control Release. 2012, 3:618-29
8.Yang T, Wang Y, Li Z, Dai W, Yin J, Liang L, Ying X, Zhou S, Wang J, Zhang X, Zhang Q*.Targeted delivery of a combination therapy consisting of combretastatin A4 and low-dose doxorubicin against tumor neovasculature. Nanomedicine: NMB, 2012, 8:81-92.