Associate Professor Li Xinru_

Associate Professor Li Xinru

Xinru Li, PhD, Associate Professor

Department of Pharmaceutics

School of Pharmaceutical Sciences

Peking University

Xueyuan Rd 38，Beijing 100191

Tel: (+8610) 82801508

Received his bachelor (1995), master degree (1998) from School of Pharmacy, Shenyang Pharmaceutical University and doctor degree (2011) from Department of Pharmaceutics, School of Pharmaceutical Sciences of Peking University. Been working in Peking Universitysince 1998. He has engaged himself in teaching of Physical Chemistry for undergraduate students, academy students and evening college students, Physical Pharmaceutical experiments course and Polymers in pharmaceuticals for graduate students. Published more than 20 research papers and 2 textbooks. Applied 10 patents.

Research Interests

 Assembly, Characterization, Evaluation and Application of Multi-functional (targeting and intelligent) Polymeric Materials

 Novel Nanosized Drug Delivery Dystem and Targeted Drug Delivery

Physical Pharmaceutics

Representative publications

1. Xinru Li, Yanqing Huang, Xingwei Chen, Yanxia Zhou, Yan Liu, et al. Self-assembly and characterization of Pluronic P105 micelles for liver-targeted delivery of silybin. Journal of Drug Targeting, 2009, 17(10):739-750.

2. Xinru Li, Yuanting Yue, Yanxia Zhou, Yan Liu, et al. An oil-free microemulsion for intravenous delivery of diallyl trisulfide: Formulation and evaluation. International Journal of Pharmaceutics, 2011, 407:158-166.

3. Xinru Li, Yanhui Zhang, Yating Fan, Yan Liu, et al. Preparation and evaluation of novel mixed micelles as nanocarriers for intravenous delivery of propofol. Nanoscale Research Letters, 2011, 6:275.

4. Xinru Li, Pingzhu Li, Yan Liu, et al. Novel mixed polymeric micelles for enhancing delivery of anticancer drug and overcoming multidrug resistance in tumor cell lines simultaneously. Pharmaceutical Research, 2010, 27(8):1498-1511.

5. Xinru Li, Xiaoyan Li, Yanxia Zhou, Yan Liu, et al. Development of patch and spray formulations for enhancing topical delivery of sinomenine hydrochloride. Journal of Pharmaceutical Sciences, 2010, 99(4):1790-1799.

6. Xinru Li, Quan Yuan, Yanqing Huang, Yanxia Zhou, and Yan Liu. Development of silymarin self-microemulsifying drug delivery system with enhanced oral bioavailability. AAPS PharmSciTech, 2010, 11(2):672-678.

7. Xinru Li, Zhuoli Yang, Kewei Yang, Yan Liu, et al. Self-assembled polymeric micellar nanoparticles as nanocarriers for poorly soluble anticancer drug ethaselen. Nanoscale Resrarch Letters, 2009, 4:1502-1511.

8. Wang Fei, Xinru Li, Zhou Yanxia, Yan Liu, et al. Novel nanoscaled polyion complex micelles for targeted delivery of recombinant hirudin to platelets based on cationic copolymer. Molecular Pharmaceutics, 2010, 7(3):718-726.

9. Yanhui Zhang, Xinru Li, Yanxia Zhou, Yan Liu, et al. Cyclosporine A-loaded poly(ethylene glycol)-b-poly(D,L-lactic acid) micelles: preparation, in vitro and in vivo characterization and transport mechanism across the intestinal barrier. Molecular Pharmaceutics, 2010, 7(4):1169-1182.

10. Ming Chen , Xinru Li, Yan-Xia Zhou, Yan Liu, et al. Improved absorption of salmon calcitonin by ultraflexible liposomes through intranasal delivery. Peptides, 2009,30:1288-1295.