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副教授 博士生导师

                                       

 

 

代文兵   博士    副教授

  电话/传真:010-82805724

电子信箱:daiwb@bjmu.edu.cn

现任药剂学系副主任。从事药物递送的教学、基础与转化研究,开设研究生课程《创新制剂转化研究》,H-index36,获得2项改良型新药的临床批件;作为主要完成人,获得1项国家科技进步二等奖和1项教育部自然科学一等奖;参加CDE新药评审会(化药和生物药),起草CDE《纳米药物质量控制研究技术指导原则》和《脂质体药物质量控制研究技术指导原则》等技术指南。

 

教育背景

2006.09-2009.07:北京大学药学院,博士

2003.09-2006.07:武汉大学药学院,硕士

1999.09-2003.07:武汉大学药学院,本科

科研与工作经历

(1) 2018.08 今:    北京大学药学院,副教授

(2) 2017.09 2018.10Johns Hopkins University,访问学者

(3) 2012.08 2018.07:北京大学药学院,助理研究员

研究兴趣

1)基于多肽自组装的药物递送

2)抗体药物递送

3)药物纳米化新策略及转化研究

代表性论文

1. Yanan Sun, Bochen Lyu, Chang Yang, Bing He, Hua Zhang, Xueqing Wang*, Qiang Zhang*, Wenbing Dai*. An enzyme-responsive and transformable PD-L1 blocking peptide-photosensitizer conjugate enables efficient photothermal immunotherapy for breast cancer, Bioactive Materials, 2023; 22: 47-59

2. Yao Lu, Ge Song, Bing He, Hua Zhang, Xueqing Wang, Demin Zhou, Wenbing Dai*, Qiang Zhang*. Strengthened Tumor Photodynamic Therapy Based on a Visible Nanoscale Covalent Organic Polymer Engineered by Microwave Assisted Synthesis. Advanced Functional Materials. 2020; 30(45): 2004834

3. Zakia Belhadj, Bing He, Hailiang Deng, Siyang Song, Hua Zhang, Xueqing Wang, Wenbing Dai*, Qiang Zhang*. A combined “eat me/don’t eat me” strategy based on extracellular vesicles for anticancer nanomedicines. Journal of Extracellular Vesicles. 2020; 9(1): 1806444

4. Binlong Chen, Wenbing Dai*, Dong Mei, Tongzhou Liu, Suxin Li, Bo He, Bing He, Lan Yuan, Hua Zhang, Xueqing Wang, Qiang Zhang*. Comprehensively priming the tumor microenvironment by cancer-associated fibroblast-targeted liposomes for combined therapy with cancer cell-targeted chemotherapeutic drug delivery system. J Control Release . 2016, 241(10): 68-80.

5. Wenbing Dai, Fang Yang, Ling Ma, Yuchen Fan, Bing He, Qihua He, Xueqing Wang, Hua Zhang, Qiang Zhang*. Combined mTOR inhibitor rapamycin and doxorubicin-loaded cyclic octapeptide modified liposomes for targeting integrin α3 in triple-negative breast cancer. Biomaterials , 2014, 35(20):5347-5358.

 

全部论文列表

http://orcid.org/0000-0002-4114-4022