代文兵 博士 副教授
电话/传真:010-82805724
电子信箱:daiwb@bjmu.edu.cn
现任药剂学系副主任。从事药物递送的教学、基础与转化研究,开设研究生课程《创新制剂转化研究》,H-index为36,获得2项改良型新药的临床批件;作为主要完成人,获得1项国家科技进步二等奖和1项教育部自然科学一等奖;参加CDE新药评审会(化药和生物药),起草CDE《纳米药物质量控制研究技术指导原则》和《脂质体药物质量控制研究技术指导原则》等技术指南。
教育背景
2006.09-2009.07:北京大学药学院,博士
2003.09-2006.07:武汉大学药学院,硕士
1999.09-2003.07:武汉大学药学院,本科
科研与工作经历
(1) 2018.08 至今: 北京大学药学院,副教授
(2) 2017.09 至2018.10:Johns Hopkins University,访问学者
(3) 2012.08 至2018.07:北京大学药学院,助理研究员
研究兴趣
(1)基于多肽自组装的药物递送
(2)抗体药物递送
(3)药物纳米化新策略及转化研究
代表性论文
1. Yanan Sun, Bochen Lyu, Chang Yang, Bing He, Hua Zhang, Xueqing Wang*, Qiang Zhang*, Wenbing Dai*. An enzyme-responsive and transformable PD-L1 blocking peptide-photosensitizer conjugate enables efficient photothermal immunotherapy for breast cancer, Bioactive Materials, 2023; 22: 47-59
2. Yao Lu, Ge Song, Bing He, Hua Zhang, Xueqing Wang, Demin Zhou, Wenbing Dai*, Qiang Zhang*. Strengthened Tumor Photodynamic Therapy Based on a Visible Nanoscale Covalent Organic Polymer Engineered by Microwave Assisted Synthesis. Advanced Functional Materials. 2020; 30(45): 2004834
3. Zakia Belhadj, Bing He, Hailiang Deng, Siyang Song, Hua Zhang, Xueqing Wang, Wenbing Dai*, Qiang Zhang*. A combined “eat me/don’t eat me” strategy based on extracellular vesicles for anticancer nanomedicines. Journal of Extracellular Vesicles. 2020; 9(1): 1806444
4. Binlong Chen, Wenbing Dai*, Dong Mei, Tongzhou Liu, Suxin Li, Bo He, Bing He, Lan Yuan, Hua Zhang, Xueqing Wang, Qiang Zhang*. Comprehensively priming the tumor microenvironment by cancer-associated fibroblast-targeted liposomes for combined therapy with cancer cell-targeted chemotherapeutic drug delivery system. J Control Release . 2016, 241(10): 68-80.
5. Wenbing Dai, Fang Yang, Ling Ma, Yuchen Fan, Bing He, Qihua He, Xueqing Wang, Hua Zhang, Qiang Zhang*. Combined mTOR inhibitor rapamycin and doxorubicin-loaded cyclic octapeptide modified liposomes for targeting integrin α3 in triple-negative breast cancer. Biomaterials , 2014, 35(20):5347-5358.
全部论文列表
http://orcid.org/0000-0002-4114-4022