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张华

副教授

张华  博士  副教授

电话/传真:(010)-82805724

电子信箱:zhangpharm@bjmu.edu.cn

 

    1996年毕业于北京医科大学药学专业,获理学学士学位。同年进入北京医科大学药学院学生办公室从事学生工作,1998~2001年推荐免试攻读北京大学药剂学硕士学位。2001年进入北京大学药学院药剂学系工作,2003年被评为讲师,2011年获得药剂学博士学位,2017年评为副教授。曾在美国肯塔基大学药学院访问学习(2008.02~2009.12)。近年来获得的奖励主要包括教育部“高等学校科学技术奖”自然科学二等奖(2006)、一等奖(2010,2011),北京大学医学部教学优秀奖(2011)等。目前主要从事药剂学的教学和科研工作,承担的教学任务有药学六年制《药剂学》和《药剂学实验》,以及夜大专科、本科的《药剂学》课程。承担自然基金青年基金一项,另外参与课题组的纵向和横向课题多项,发表论文五十余篇,获得专利授权两项。

 

研究方向:

纳米药物给药系统,包括脂质体、纳米粒、胶束和药物的纳米晶体等

 

发表论文:

1. Bo He , Dan Yang, Mengmeng Qin, Yuan Zhang, Bing He , Wenbing Dai, Xueqing Wang , Qiang Zhang , Hua Zhang *, Changcheng Yin* Increased cellular uptake of peptide-modified PEGylated gold nanoparticles. Biochemical and Biophysical Research Communications 2017,494:339-345

2.Hongxiang Hu, Zhiqiang Lin, Bing He, Zhang, Wenbing Dai, Xueqing Wang, Jiancheng Wang, Xuan Zhang, Hua Zhang*, Qiang Zhang*. A novel localized co-delivery system with lapatinib microparticles and paclitaxel nanoparticles in a peritumorally injectable in situ hydrogel. Journal of Controlled Release. 2015, 220: 189-200.

3. Hua Zhang, Hongxiang Hu, Haoran Zhang, Wenbing Dai, Xinglin Wang, Xueqing Wang*, Qiang Zhang*. Effects of PEGylated paclitaxel nanocrystals in breast cancer and its lung metastasis. Nanoscale. 2015, 7(24): 10790-10800.

4. Hua Zhang, Xueqing Wang, Wenbing Dai, Richard A. Gemeinhart, Qiang Zhang*, Tonglei Li*. Pharmacokinetics and treatment efficacy of camptothecin nanocrystals on lung metastasis. Molecular Pharmaceutics. 2014, 11(1): 226-233.

5. Hua Zhang, Yuan Meng, Xueqing Wang, Wenbing Dai, Xinglin Wang, Qiang Zhang*. Pharmaceutical and pharmacpkinetic characteristics of different types of fenofibrate nanocrystals prepared by different bottom-up approuches. Drug Delivery. 2014, 21(8): 588-594.

6. Hua Zhang, Youyou Zhao, Xueqing Wang*, Qiang Zhang. Bioavailability of tramadol hydrochloride after administration via different routes in rats. Biopharmaceutics & Drug Disposition. 2014, 35(9): 525-531.

7. Hua Zhang; P.Cristine Hollis; Qiang Zhang*; Tonglei Li*. Preparation and antitumor study of camptothecin nanocrystals. Int. J. Pharm. 2011,415(1-2): 293-300.